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The higher discontinuation rate among patients with obesity raises questions about whether weight loss or adverse effects drive this trend

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World J Gastroenterol 20:17681776

Berberine and drug metabolism : Berberine inhibits several enzymes (particularly CYP3A4, CYP2D6, and CYP2C9) and transport proteins (P-glycoprotein) that metabolise many medications

CaMK4 regulates two crucial aspects of homoeostatic plasticity: excitatory synaptic scaling and intrinsic excitability [104, 106]